STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2199Identified by match to protein family HMM PF03739. (357 aa)    
Predicted Functional Partners:
AFE_2200
Identified by match to protein family HMM PF03739.
 
 0.999
AFE_3026
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 
 0.992
AFE_3028
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.909
AFE_2197
Hypothetical protein; Identified by glimmer; putative.
       0.773
lptD
Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
 
  
 0.707
holC
DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364.
 
     0.661
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
       0.593
lpxB
Lipid A disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
     0.556
lpxA
acyl-(acyl-carrier-protein)-UDP-N- acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.514
AFE_0159
Toluene tolerance protein Ttg2B, putative; Identified by similarity to GB:AAD17958.1; match to protein family HMM PF02405; match to protein family HMM TIGR00056.
  
 
 0.500
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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