Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2212Conserved hypothetical protein; Identified by similarity to GB:AAM38230.1. (208 aa)    
Predicted Functional Partners:
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
     0.634
AFE_0906
Conserved hypothetical protein; Identified by similarity to SP:P45576.
  
     0.633
AFE_0649
Identified by match to protein family HMM PF03372.
  
     0.579
AFE_0166
HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.
  
     0.570
AFE_2745
Conserved hypothetical protein; Identified by similarity to PIR:S61401.
  
     0.536
AFE_1152
HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.
  
     0.533
AFE_2345
ATP-dependent protease La domain protein; Identified by similarity to GB:AAN70383.1; match to protein family HMM PF02190.
  
     0.501
AFE_2214
Conserved hypothetical protein; Identified by similarity to GB:AAM40463.1; match to protein family HMM PF05656.
       0.488
AFE_1915
Type IV pilus assembly protein PilZ, putative; Identified by similarity to PIR:B59241; match to protein family HMM PF07238.
  
     0.470
AFE_0736
Type 4 fimbrial biogenesis protein PilP, putative; Identified by similarity to GB:AAA93089.1.
 
     0.449
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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