rluC protein (Acidithiobacillus ferrooxidans)

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rluC

Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (317 aa)

Predicted Functional Partners:

rplC

0.842

AFE_2218

0.821

rplO

0.793

AFE_0991

0.786

rplQ

0.778

rsfS

0.771

rplK

0.764

rplU

0.757

rplM

0.751

rplN

0.742

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0991	rluC	AFE_0991	AFE_2219	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	0.786
AFE_0991	rplC	AFE_0991	AFE_0327	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.846
AFE_0991	rplK	AFE_0991	AFE_0315	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.929
AFE_0991	rplM	AFE_0991	AFE_3075	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.864
AFE_0991	rplN	AFE_0991	AFE_0337	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.773
AFE_0991	rplO	AFE_0991	AFE_0346	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.818
AFE_0991	rplQ	AFE_0991	AFE_0355	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L17; Identified by similarity to SP:P02416; match to protein family HMM PF01196; match to protein family HMM TIGR00059.	0.817
AFE_0991	rplU	AFE_0991	AFE_0285	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.829
AFE_0991	rsfS	AFE_0991	AFE_2949	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.815
AFE_2218	rluC	AFE_2218	AFE_2219	HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	0.821
rluC	AFE_0991	AFE_2219	AFE_0991	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.786
rluC	AFE_2218	AFE_2219	AFE_2218	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.	0.821
rluC	rplC	AFE_2219	AFE_0327	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.842
rluC	rplK	AFE_2219	AFE_0315	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.764
rluC	rplM	AFE_2219	AFE_3075	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.751
rluC	rplN	AFE_2219	AFE_0337	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.742
rluC	rplO	AFE_2219	AFE_0346	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.793
rluC	rplQ	AFE_2219	AFE_0355	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L17; Identified by similarity to SP:P02416; match to protein family HMM PF01196; match to protein family HMM TIGR00059.	0.778
rluC	rplU	AFE_2219	AFE_0285	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.757
rluC	rsfS	AFE_2219	AFE_2949	Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.	Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.771

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