Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2226Conserved domain protein; Identified by match to protein family HMM PF01636. (560 aa)    
Predicted Functional Partners:
AFE_2227
HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM PF00702.
 
     0.868
AFE_2019
Conserved domain protein.
  
     0.631
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.585
AFE_2224
Glycosyl hydrolase, family 15; Identified by match to protein family HMM PF00723; match to protein family HMM PF09137.
 
     0.559
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.559
AFE_2223
Penicillin-binding protein 1A, putative; Identified by similarity to SP:P31776; match to protein family HMM PF00905; match to protein family HMM PF00912.
 
     0.542
AFE_2225
Glucose 1-dehydrogenase, putative; Identified by similarity to SP:P39482; match to protein family HMM PF00106; match to protein family HMM PF08659.
  
 
 0.506
AFE_1832
Hypothetical protein; Identified by glimmer; putative.
  
     0.472
AFE_1218
Conserved domain protein; Identified by similarity to PIR:A97990.
  
     0.463
AFE_0100
Conserved hypothetical protein; Identified by similarity to GB:AAM71795.1; match to protein family HMM PF00529.
  
     0.462
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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