close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnK-2Nitrogen regulatory protein P-II 2; Identified by similarity to SP:P38504; match to protein family HMM PF00543. (132 aa)    
Predicted Functional Partners:
AFE_2241
Hypothetical protein; Identified by glimmer; putative.
       0.773
amtB
Identified by match to protein family HMM PF00909.
  
 
 0.708
amt-2
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
  
 
 0.708
amt-1
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
  
 
 0.708
glnD
protein-P-II uridylyltransferase; Identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF08335; match to protein family HMM TIGR01693.
 
 
 
 0.676
argA
N-acetylglutamate synthase; Identified by similarity to SP:P08205; match to protein family HMM PF00583; match to protein family HMM PF00696; match to protein family HMM TIGR01890; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.623
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.609
AFE_2239
Hypothetical protein; Identified by glimmer; putative.
       0.601
AFE_2242
Hypothetical protein; Identified by glimmer; putative.
       0.594
ntrB
Nitrogen regulation protein NR(II); Identified by similarity to SP:P06218; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF08448.
  
 
 0.594
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]