Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2250Carbohydrate-selective porin, OprB family; Identified by match to protein family HMM PF04966. (373 aa)    
Predicted Functional Partners:
AFE_2251
PQQ enzyme repeat domain protein; Identified by similarity to SP:P54741.
       0.757
tadB
Tight adherence protein TadB, putative; Identified by similarity to GB:AAO10168.1; match to protein family HMM PF00482.
      
 0.707
AFE_0076
Polysaccharide biosynthesis protein; Identified by similarity to SP:P37781; match to protein family HMM PF01943.
  
     0.584
AFE_1695
Conjugal transfer protein; Identified by similarity to SP:P54915; match to protein family HMM PF03524.
  
     0.584
AFE_1881
Hypothetical protein; Identified by glimmer; putative.
  
     0.575
AFE_2993
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
  
     0.572
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.561
AFE_2117
Membrane protein, putative; Identified by match to protein family HMM TIGR00374; match to protein family HMM TIGR03476.
  
     0.547
AFE_1698
Conjugal transfer -like protein; Identified by match to protein family HMM PF01464.
  
     0.543
AFE_2161
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
  
     0.517
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.