STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2256Identified by match to protein family HMM PF00753. (263 aa)    
Predicted Functional Partners:
hemN
Oxygen-independent coproporphyrinogen III oxidase; Identified by similarity to SP:P32131; match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.789
AFE_2255
Hypothetical protein; Identified by glimmer; putative.
       0.715
AFE_0859
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
  
  
 0.549
AFE_2257
Conserved hypothetical protein.
       0.482
AFE_2258
Membrane protein, putative; Identified by match to protein family HMM PF01925.
       0.482
AFE_1792
Sulfide-quinone reductase, putative; Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Consecutive reaction cycles lead to the accumulation of a polysulfide product on the active site Cys residues; these products are released when they exceed a critical length, typically as cyclooctasulfur; Belongs to the SQRD family.
 
    0.458
AFE_2385
SCP-2 sterol transfer family protein; Identified by match to protein family HMM PF02036.
  
     0.457
AFE_2259
Identified by match to protein family HMM PF00582.
       0.434
AFE_2868
Conserved hypothetical protein; Identified by similarity to PIR:D70379; match to protein family HMM PF01814.
 
  
 0.421
AFE_1508
Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.417
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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