AFE_2312 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1575	AFE_1577	AFE_1575	AFE_1577	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	0.989
AFE_1575	AFE_1636	AFE_1575	AFE_1636	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Hypothetical protein; Identified by glimmer; putative.	0.707
AFE_1575	AFE_1651	AFE_1575	AFE_1651	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Identified by similarity to SP:O34969; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.707
AFE_1575	AFE_1652	AFE_1575	AFE_1652	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Oxidoreductase alpha (molybdopterin) subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01701; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.604
AFE_1575	AFE_2312	AFE_1575	AFE_2312	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.613
AFE_1575	AFE_2393	AFE_1575	AFE_2393	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	ISAfe5, transposase orfA; Identified by similarity to GB:AAB81643.1.	0.707
AFE_1575	AFE_3223	AFE_1575	AFE_3223	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	WrbA family protein; Identified by similarity to SP:P30849; Belongs to the WrbA family.	0.604
AFE_1575	dinJ	AFE_1575	AFE_1589	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	DNA-damage-inducible protein J; Identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384.	0.468
AFE_1575	fdhD-1	AFE_1575	AFE_1654	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.	0.466
AFE_1577	AFE_1575	AFE_1577	AFE_1575	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	0.989
AFE_1577	AFE_1636	AFE_1577	AFE_1636	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Hypothetical protein; Identified by glimmer; putative.	0.707
AFE_1577	AFE_1651	AFE_1577	AFE_1651	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Identified by similarity to SP:O34969; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.707
AFE_1577	AFE_1652	AFE_1577	AFE_1652	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Oxidoreductase alpha (molybdopterin) subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01701; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.604
AFE_1577	AFE_2312	AFE_1577	AFE_2312	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.610
AFE_1577	AFE_2393	AFE_1577	AFE_2393	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	ISAfe5, transposase orfA; Identified by similarity to GB:AAB81643.1.	0.707
AFE_1577	AFE_3223	AFE_1577	AFE_3223	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	WrbA family protein; Identified by similarity to SP:P30849; Belongs to the WrbA family.	0.604
AFE_1577	dinJ	AFE_1577	AFE_1589	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	DNA-damage-inducible protein J; Identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384.	0.468
AFE_1577	fdhD-1	AFE_1577	AFE_1654	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.	0.466
AFE_1636	AFE_1575	AFE_1636	AFE_1575	Hypothetical protein; Identified by glimmer; putative.	Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.	0.707
AFE_1636	AFE_1577	AFE_1636	AFE_1577	Hypothetical protein; Identified by glimmer; putative.	Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.	0.707