Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2316Outer membrane lipoprotein Slp, putative; Identified by similarity to SP:P37194; match to protein family HMM PF03843. (178 aa)    
Predicted Functional Partners:
smg
Smg family protein; Belongs to the Smg family.
  
     0.682
AFE_2318
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
       0.508
AFE_2830
Conserved hypothetical protein; Identified by similarity to GB:CAD85351.1.
  
     0.508
AFE_2319
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
       0.476
AFE_2831
Hypothetical protein; Identified by glimmer; putative.
  
     0.466
AFE_0549
Conserved hypothetical protein; Identified by similarity to PIR:E82325.
  
     0.462
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
     0.442
sixA
Phosphohistidine phosphatase SixA; Identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249.
  
    0.419
AFE_2313
Hypothetical protein; Identified by glimmer; putative.
       0.409
AFE_2564
Rod shape-determining protein MreD, putative; Identified by similarity to SP:P16927; match to protein family HMM TIGR03426.
  
     0.409
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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