AFE_2323 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AFE_2323

Conserved hypothetical protein; Identified by similarity to PIR:T35630. (296 aa)

Predicted Functional Partners:

AFE_2322

0.912

AFE_2321

0.902

AFE_2677

0.744

AFE_2325

0.737

AFE_2552

0.687

AFE_0860

0.603

AFE_0721

0.592

AFE_2324

0.592

AFE_2352

0.568

AFE_2535

0.567

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
AFE_0721	AFE_2321	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	0.405
AFE_0721	AFE_2323	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	0.592
AFE_0721	AFE_2325	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Hypothetical protein; Identified by glimmer; putative.	0.572
AFE_0721	AFE_2352	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Conserved hypothetical protein; Identified by similarity to GB:BAC47910.1; match to protein family HMM PF00891; match to protein family HMM PF08241; match to protein family HMM PF08242.	0.540
AFE_0721	AFE_2535	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Von Willebrand factor type A domain protein.	0.474
AFE_0721	AFE_2552	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	Conserved hypothetical protein; Identified by similarity to PIR:H70335.	0.620
AFE_0721	AFE_2677	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	3-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.713
AFE_0860	AFE_2323	Iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	0.603
AFE_2321	AFE_0721	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Conserved hypothetical protein; Identified by similarity to PIR:A97389.	0.405
AFE_2321	AFE_2322	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Conserved hypothetical protein; Identified by similarity to SP:Q11166; match to protein family HMM PF01073; match to protein family HMM PF01370.	0.898
AFE_2321	AFE_2323	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	0.902
AFE_2321	AFE_2324	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.564
AFE_2321	AFE_2325	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Hypothetical protein; Identified by glimmer; putative.	0.573
AFE_2321	AFE_2352	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Conserved hypothetical protein; Identified by similarity to GB:BAC47910.1; match to protein family HMM PF00891; match to protein family HMM PF08241; match to protein family HMM PF08242.	0.411
AFE_2321	AFE_2552	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	Conserved hypothetical protein; Identified by similarity to PIR:H70335.	0.569
AFE_2321	AFE_2677	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	3-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.	0.704
AFE_2322	AFE_2321	Conserved hypothetical protein; Identified by similarity to SP:Q11166; match to protein family HMM PF01073; match to protein family HMM PF01370.	Monooxygenase, luciferase-like protein; Identified by match to protein family HMM PF00296.	0.898
AFE_2322	AFE_2323	Conserved hypothetical protein; Identified by similarity to SP:Q11166; match to protein family HMM PF01073; match to protein family HMM PF01370.	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	0.912
AFE_2322	AFE_2324	Conserved hypothetical protein; Identified by similarity to SP:Q11166; match to protein family HMM PF01073; match to protein family HMM PF01370.	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.543
AFE_2322	AFE_2325	Conserved hypothetical protein; Identified by similarity to SP:Q11166; match to protein family HMM PF01073; match to protein family HMM PF01370.	Hypothetical protein; Identified by glimmer; putative.	0.593