AFE_2324 protein (Acidithiobacillus ferrooxidans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0527	AFE_1799	AFE_0527	AFE_1799	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	0.900
AFE_0527	AFE_2324	AFE_0527	AFE_2324	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.982
AFE_0527	galU	AFE_0527	AFE_0445	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	UTP-glucose-1-phosphate uridylyltransferase; Identified by similarity to SP:Q05852; match to protein family HMM PF00483; match to protein family HMM TIGR01099.	0.910
AFE_0527	glgC	AFE_0527	AFE_2838	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	0.991
AFE_0527	pgi	AFE_0527	AFE_2924	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family.	0.522
AFE_1799	AFE_0527	AFE_1799	AFE_0527	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.900
AFE_1799	AFE_2324	AFE_1799	AFE_2324	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	0.979
AFE_1799	galU	AFE_1799	AFE_0445	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	UTP-glucose-1-phosphate uridylyltransferase; Identified by similarity to SP:Q05852; match to protein family HMM PF00483; match to protein family HMM TIGR01099.	0.910
AFE_1799	glgC	AFE_1799	AFE_2838	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	0.984
AFE_1799	pgi	AFE_1799	AFE_2924	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family.	0.522
AFE_2324	AFE_0527	AFE_2324	AFE_0527	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.982
AFE_2324	AFE_1799	AFE_2324	AFE_1799	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094.	0.979
AFE_2324	AFE_2841	AFE_2324	AFE_2841	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	ROK family protein; Identified by match to protein family HMM PF00480.	0.914
AFE_2324	galU	AFE_2324	AFE_0445	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	UTP-glucose-1-phosphate uridylyltransferase; Identified by similarity to SP:Q05852; match to protein family HMM PF00483; match to protein family HMM TIGR01099.	0.939
AFE_2324	glgC	AFE_2324	AFE_2838	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	0.950
AFE_2324	pgi	AFE_2324	AFE_2924	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342; Belongs to the GPI family.	0.989
AFE_2324	rpiA	AFE_2324	AFE_0629	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.	0.921
AFE_2324	tkt-1	AFE_2324	AFE_1843	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; Belongs to the transketolase family.	0.927
AFE_2324	tkt-2	AFE_2324	AFE_3252	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Transketolase; Identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; Belongs to the transketolase family.	0.927
AFE_2324	zwf	AFE_2324	AFE_2025	Phosphoglucomutase, putative; Identified by similarity to SP:P39671; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.	0.913