Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2372Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497. (537 aa)    
Predicted Functional Partners:
AFE_2378
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
 
 0.974
AFE_2374
Anticodon nuclease, putative; Identified by similarity to SP:P17223.
 
     0.947
AFE_2381
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.861
AFE_0829
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
   0.853
AFE_0841
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.791
AFE_2373
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_2375
ATP-dependent helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
 
     0.628
AFE_0686
Type I restriction-modification system, S subunit, putative; Identified by similarity to SP:P19704; match to protein family HMM PF01420.
  
 
 0.613
AFE_2791
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
  
   0.582
AFE_2371
Hypothetical protein; Identified by glimmer; putative.
       0.580
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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