Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2375ATP-dependent helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. (1054 aa)    
Predicted Functional Partners:
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
 0.960
AFE_1637
Conjugal transfer protein TrbD, putative.
  
 
 0.870
AFE_2378
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
     0.837
ppiB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.817
AFE_2377
Hypothetical protein; Identified by glimmer; putative.
       0.799
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.745
deaD
ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 0.711
rhlE
ATP-dependent RNA helicase RhlE; Identified by similarity to SP:P25888; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family.
    
 0.711
AFE_2374
Anticodon nuclease, putative; Identified by similarity to SP:P17223.
 
     0.667
AFE_2372
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497.
 
     0.628
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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