Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2390Conserved hypothetical protein; Identified by similarity to GB:AAQ61663.1. (87 aa)    
Predicted Functional Partners:
ubiH-2
2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01494; match to protein family HMM TIGR01988.
 
   
 0.791
ubiH-1
2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988.
     
 0.758
AFE_3096
Conserved hypothetical protein; Identified by similarity to GB:AAQ58453.1.
  
     0.533
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
 
     0.513
AFE_2386
Identified by match to protein family HMM PF00899.
       0.496
AFE_2387
Hydrolase, TatD family; Identified by match to protein family HMM PF01026.
       0.496
AFE_0850
Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.483
AFE_2384
Conserved hypothetical protein; Identified by similarity to PIR:A82245.
 
     0.467
AFE_2675
Conserved hypothetical protein; Identified by similarity to GB:CAD84648.1.
  
     0.462
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
  
     0.456
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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