Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_2407Conserved hypothetical protein; Identified by similarity to GB:AAN30751.1. (431 aa)    
Predicted Functional Partners:
AFE_2408
DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851.
  
    0.780
AFE_0007
Outer membrane usher protein, putative; Identified by match to protein family HMM PF00577.
      
 0.723
hslO
33 kDa chaperonin; Identified by similarity to SP:P45803; match to protein family HMM PF01430.
      
 0.723
AFE_2920
Conserved hypothetical protein; Identified by similarity to GB:AAM72618.1.
      
 0.723
cyoB
Cytochrome o ubiquinol oxidase, subunit I; Identified by similarity to SP:P18401; match to protein family HMM PF00115; Belongs to the heme-copper respiratory oxidase family.
      
 0.461
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.460
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
      
 0.440
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
   
  
 0.402
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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