Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AFE_2429[Ni/Fe] hydrogenase, b-type cytochrome subunit, putative; Identified by match to protein family HMM PF01292. (251 aa)    
Predicted Functional Partners:
hynL
[Ni/Fe] hydrogenase, large subunit; Identified by similarity to GB:AAC38282.1; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.964
hynS
[Ni/Fe] hydrogenase, small subunit; Identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409.
 
 
 0.914
hybC
Hydrogenase-2, large subunit; Identified by match to protein family HMM PF00374.
 
 
 0.907
hybA
Hydrogenase-2, small subunit; Identified by match to protein family HMM PF01058.
 
 
 0.795
AFE_2430
Conserved hypothetical protein; Identified by similarity to GB:BAB47830.1; match to protein family HMM PF01987.
 
     0.714
AFE_2428
Heavy metal efflux system protein, putative; Identified by similarity to SP:P77214.
 
     0.666
hynD
Hydrogenase maturation protease; Identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072.
 
  
 0.648
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.567
hynH
Hydrogenase expression protein, putative.
  
     0.559
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.555
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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