Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2434Outer membrane efflux protein; Identified by match to protein family HMM PF02321. (433 aa)    
Predicted Functional Partners:
AFE_2433
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.957
AFE_1949
Outer membrane heavy metal efflux protein, putative; Identified by similarity to SP:P11092; match to protein family HMM PF02321.
  
  
 
0.900
AFE_1948
Heavy metal efflux transporter, MFP subunit, putative; Identified by similarity to SP:P77239; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.820
AFE_1947
Heavy metal efflux pump, CzcA family; Identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.810
AFE_2431
Heavy metal efflux pump, CzcA family; Identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.810
AFE_2135
Identified by match to protein family HMM PF02470.
 
   
 0.764
AFE_2428
Heavy metal efflux system protein, putative; Identified by similarity to SP:P77214.
 
   0.736
AFE_0160
Identified by match to protein family HMM PF02470.
     
 0.725
AFE_2782
Cation efflux system protein, putative; Identified by similarity to SP:P77214.
 
   0.657
AFE_2036
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.557
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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