Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2450Identified by match to protein family HMM PF00034. (100 aa)    
Predicted Functional Partners:
AFE_1962
Identified by match to protein family HMM PF00034.
  
  
 
0.909
AFE_2034
Conserved domain protein; Identified by similarity to GB:AAM05308.1.
  
  
 0.630
AFE_2452
Hypothetical protein; Identified by glimmer; putative.
       0.625
gshA
Glutamate--cysteine ligase; Identified by match to protein family HMM PF08886; match to protein family HMM TIGR02049.
  
     0.524
AFE_2448
Heavy metal-binding protein, putative; Identified by match to protein family HMM PF00403.
       0.480
AFE_2449
Conserved hypothetical protein; Identified by similarity to PIR:B75601; match to protein family HMM PF00462; match to protein family HMM PF05768.
       0.480
AFE_0398
Conserved hypothetical protein; Identified by similarity to GB:CAD15216.1.
  
     0.460
AFE_2868
Conserved hypothetical protein; Identified by similarity to PIR:D70379; match to protein family HMM PF01814.
  
     0.406
AFE_2428
Heavy metal efflux system protein, putative; Identified by similarity to SP:P77214.
  
     0.400
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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