Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
merCMercuric resistance protein MerC; Identified by similarity to SP:P22905; match to protein family HMM PF03203. (144 aa)    
Predicted Functional Partners:
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
  
 0.915
cga
Glucan 1,4-alpha-glucosidase; Identified by match to protein family HMM PF00723; match to protein family HMM PF09137.
       0.537
arsR
Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022.
      
 0.449
arsH
Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family.
      
 0.440
arsB
Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935.
      
 0.440
AFE_2478
Hypothetical protein; Identified by glimmer; putative.
       0.424
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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