Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2532Hypothetical protein; Identified by glimmer; putative. (200 aa)    
Predicted Functional Partners:
nrdA
Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
      
 0.722
AFE_2529
Hypothetical protein; Identified by glimmer; putative.
       0.584
AFE_2530
Conserved hypothetical protein; Identified by similarity to GB:AAQ61408.1.
       0.583
AFE_2531
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
       0.573
AFE_2527
Membrane protein, DedA family; Identified by similarity to GB:AAN66167.1; match to protein family HMM PF09335.
       0.486
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
      
 0.467
sixA
Phosphohistidine phosphatase SixA; Identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249.
      
 0.466
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
      
 0.444
AFE_0569
Identified by match to protein family HMM PF03734.
      
 0.440
AFE_0998
Transcriptional regulator, putative; Identified by similarity to SP:Q06553; match to protein family HMM PF00717; match to protein family HMM PF01381; match to protein family HMM PF07022.
      
 0.440
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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