Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2533Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248. (381 aa)    
Predicted Functional Partners:
AFE_2534
Identified by match to protein family HMM PF00850.
 
 
  0.937
AFE_2535
Von Willebrand factor type A domain protein.
 
     0.809
AFE_2552
Conserved hypothetical protein; Identified by similarity to PIR:H70335.
 
     0.791
AFE_2548
Conserved hypothetical protein; Identified by similarity to PIR:A83048.
 
     0.784
AFE_2543
Radical SAM domain protein; Identified by match to protein family HMM PF04055.
 
     0.773
AFE_2546
Radical SAM domain protein; Identified by match to protein family HMM PF04055.
 
     0.767
AFE_2554
Heterodisulfide reductase subunit B, homolog; Identified by similarity to PIR:H90265; match to protein family HMM PF02754.
 
     0.764
AFE_2551
Iron-sulfur cluster-binding protein.
 
     0.743
AFE_0363
Conserved hypothetical protein; Identified by similarity to PIR:C70335.
  
     0.742
AFE_2555
Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037.
 
     0.737
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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