Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2535Von Willebrand factor type A domain protein. (805 aa)    
Predicted Functional Partners:
AFE_2536
CbbQ/NirQ/NorQ/GpvN family protein; Identified by similarity to SP:Q02441; similarity to SP:Q51858; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.942
p30
P30 protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.879
cbbQ-1
CbbQ protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.879
cbbQ-2
CbbQ protein; Identified by similarity to GB:BAA76361.1; match to protein family HMM PF07728; match to protein family HMM PF08406.
 
 
 0.878
AFE_2533
Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248.
 
     0.809
AFE_2534
Identified by match to protein family HMM PF00850.
 
     0.715
AFE_2677
3-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
     0.710
AFE_1297
Cobalamin biosynthesis protein, CobS family; Identified by match to protein family HMM PF07728.
 
 
 0.688
AFE_2552
Conserved hypothetical protein; Identified by similarity to PIR:H70335.
 
     0.620
AFE_2537
Hypothetical protein; Identified by glimmer; putative.
       0.588
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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