Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mreCRod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (279 aa)    
Predicted Functional Partners:
mreB
Rod shape-determining protein MreB; Identified by similarity to SP:P13519; match to protein family HMM PF06723; match to protein family HMM TIGR00904.
 
 
 0.992
AFE_2564
Rod shape-determining protein MreD, putative; Identified by similarity to SP:P16927; match to protein family HMM TIGR03426.
  
 
 0.987
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall.
 
 
 0.966
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
  
 0.958
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.884
AFE_1323
Hypothetical protein; Identified by glimmer; putative.
  
 
 0.884
AFE_2144
Penicillin-binding protein 2, putative; Identified by similarity to SP:P08150; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423.
 
 
 0.854
radC
DNA repair protein RadC; Identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
  
 0.843
minD
Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968.
  
    0.804
AFE_2567
D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P04287; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
  
  
 0.683
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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