Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2567D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P04287; match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family. (388 aa)    
Predicted Functional Partners:
AFE_2350
D-alanyl-D-alanine carboxypeptidase, putative; Identified by similarity to SP:P08506; match to protein family HMM PF00768; Belongs to the peptidase S11 family.
  
  
 
0.917
AFE_2923
D-alanyl-D-alanine carboxypeptidase; Identified by similarity to SP:P08506; match to protein family HMM PF00768; Belongs to the peptidase S11 family.
  
  
 
0.910
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by similarity to SP:P24228; match to protein family HMM PF02113; match to protein family HMM TIGR00666.
     
 0.909
AFE_2172
Beta-lactamase; Identified by match to protein family HMM PF00144.
     
 0.909
AFE_2223
Penicillin-binding protein 1A, putative; Identified by similarity to SP:P31776; match to protein family HMM PF00905; match to protein family HMM PF00912.
     
 0.909
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
   
 0.768
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall.
  
  
 0.721
mreB
Rod shape-determining protein MreB; Identified by similarity to SP:P13519; match to protein family HMM PF06723; match to protein family HMM TIGR00904.
 
  
 0.718
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.683
AFE_2564
Rod shape-determining protein MreD, putative; Identified by similarity to SP:P16927; match to protein family HMM TIGR03426.
     
 0.679
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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