| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| coaE | tldD | AFE_0187 | AFE_2637 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.589 |
| folP | ftsH | AFE_2635 | AFE_2636 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.867 |
| folP | glmM | AFE_2635 | AFE_2634 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.794 |
| folP | tldD | AFE_2635 | AFE_2637 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.551 |
| ftsH | folP | AFE_2636 | AFE_2635 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.867 |
| ftsH | glmM | AFE_2636 | AFE_2634 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.733 |
| ftsH | tldD | AFE_2636 | AFE_2637 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.595 |
| glmM | folP | AFE_2634 | AFE_2635 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.794 |
| glmM | ftsH | AFE_2634 | AFE_2636 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.733 |
| glmM | tldD | AFE_2634 | AFE_2637 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.461 |
| nrdB | tldD | AFE_2639 | AFE_2637 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.423 |
| pmbA | tldD | AFE_0600 | AFE_2637 | pmbA protein; Identified by similarity to SP:P24231; match to protein family HMM PF01523. | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | 0.898 |
| tldD | coaE | AFE_2637 | AFE_0187 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.589 |
| tldD | folP | AFE_2637 | AFE_2635 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.551 |
| tldD | ftsH | AFE_2637 | AFE_2636 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.595 |
| tldD | glmM | AFE_2637 | AFE_2634 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.461 |
| tldD | nrdB | AFE_2637 | AFE_2639 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.423 |
| tldD | pmbA | AFE_2637 | AFE_0600 | tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523. | pmbA protein; Identified by similarity to SP:P24231; match to protein family HMM PF01523. | 0.898 |