nrdA protein (Acidithiobacillus ferrooxidans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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co-expression

Genomic Predictions

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gene co-occurrence

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Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0367	AFE_3062	AFE_0367	AFE_3062	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Conserved hypothetical protein; Identified by similarity to GB:BAC60875.1; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.	0.593
AFE_0367	nrdA	AFE_0367	AFE_2638	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.901
AFE_3062	AFE_0367	AFE_3062	AFE_0367	Conserved hypothetical protein; Identified by similarity to GB:BAC60875.1; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	0.593
AFE_3062	grxC	AFE_3062	AFE_2363	Conserved hypothetical protein; Identified by similarity to GB:BAC60875.1; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	0.500
AFE_3062	nrdA	AFE_3062	AFE_2638	Conserved hypothetical protein; Identified by similarity to GB:BAC60875.1; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.	Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.975
adk	cmk	AFE_0348	AFE_0902	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	0.441
adk	gmk	AFE_0348	AFE_0563	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.831
adk	ndk	AFE_0348	AFE_1929	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.955
adk	nrdA	AFE_0348	AFE_2638	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.922
adk	nrdB	AFE_0348	AFE_2639	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.930
adk	tmk	AFE_0348	AFE_1913	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.424
cmk	adk	AFE_0902	AFE_0348	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.441
cmk	gmk	AFE_0902	AFE_0563	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.552
cmk	ndk	AFE_0902	AFE_1929	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.934
cmk	nrdA	AFE_0902	AFE_2638	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.919
cmk	nrdB	AFE_0902	AFE_2639	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.927
gmk	adk	AFE_0563	AFE_0348	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.831
gmk	cmk	AFE_0563	AFE_0902	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.	0.552
gmk	ndk	AFE_0563	AFE_1929	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.922
gmk	nrdA	AFE_0563	AFE_2638	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.907