Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2641Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022. (113 aa)    
Predicted Functional Partners:
AFE_2642
Membrane protein, putative; Identified by match to protein family HMM PF07690.
 
     0.808
AFE_2643
Conserved hypothetical protein; Identified by similarity to GB:AAK02599.1.
       0.774
AFE_2640
Hypothetical protein; Identified by glimmer; putative.
       0.762
AFE_2369
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022.
  
     0.739
AFE_2026
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022.
  
     0.725
AFE_2644
Identified by match to protein family HMM PF00753.
       0.605
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
   
 0.508
AFE_2209
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
      
 0.457
AFE_0582
Conserved hypothetical protein; Identified by similarity to GB:AAL62784.1.
      
 0.448
proB-1
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
      
 0.448
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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