Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2659Amino acid permease family protein; Identified by match to protein family HMM PF00324. (468 aa)    
Predicted Functional Partners:
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.595
AFE_2658
Conserved hypothetical protein; Identified by similarity to GB:AAM81143.1.
       0.588
AFE_0439
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
  
     0.578
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.578
AFE_1497
Conserved hypothetical protein; Identified by match to protein family HMM PF03573.
  
    0.575
AFE_2457
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
  
     0.574
AFE_1782
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
  
     0.563
AFE_3296
Major facilitator family transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
     0.560
AFE_2292
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.558
AFE_2019
Conserved domain protein.
  
     0.554
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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