AFE_2662 protein (Acidithiobacillus ferrooxidans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_2323	AFE_2662	AFE_2323	AFE_2662	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	0.453
AFE_2662	AFE_2323	AFE_2662	AFE_2323	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Conserved hypothetical protein; Identified by similarity to PIR:T35630.	0.453
AFE_2662	dapB	AFE_2662	AFE_2663	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	0.709
AFE_2662	dcd	AFE_2662	AFE_2660	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	0.683
AFE_2662	dnaJ	AFE_2662	AFE_2664	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.688
AFE_2662	dnaK	AFE_2662	AFE_2665	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.517
AFE_2662	grpE	AFE_2662	AFE_2666	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.432
AFE_2662	hemG	AFE_2662	AFE_0570	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.417
AFE_2662	mrp	AFE_2662	AFE_2661	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.776
dapB	AFE_2662	AFE_2663	AFE_2662	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	0.709
dapB	dcd	AFE_2663	AFE_2660	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	0.606
dapB	dnaJ	AFE_2663	AFE_2664	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.959
dapB	dnaK	AFE_2663	AFE_2665	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.675
dapB	grpE	AFE_2663	AFE_2666	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.649
dapB	mrp	AFE_2663	AFE_2661	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.701
dcd	AFE_2662	AFE_2660	AFE_2662	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992.	0.683
dcd	dapB	AFE_2660	AFE_2663	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.	0.606
dcd	dnaJ	AFE_2660	AFE_2664	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.618
dcd	dnaK	AFE_2660	AFE_2665	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.453
dcd	mrp	AFE_2660	AFE_2661	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.	0.731