Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2675Conserved hypothetical protein; Identified by similarity to GB:CAD84648.1. (162 aa)    
Predicted Functional Partners:
AFE_0546
Conserved hypothetical protein; Identified by similarity to GB:AAO91158.1.
  
     0.763
AFE_0444
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.708
AFE_0130
Conserved hypothetical protein; Identified by similarity to GB:AAM35577.1; match to protein family HMM PF02636.
  
     0.705
AFE_2674
Oligoendopeptidase F, putative; Identified by similarity to SP:P94876; match to protein family HMM PF01432; match to protein family HMM PF08439.
       0.647
AFE_1769
Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
  
     0.644
AFE_0398
Conserved hypothetical protein; Identified by similarity to GB:CAD15216.1.
  
     0.636
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.636
AFE_2494
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.633
AFE_0471
Conserved hypothetical protein; Identified by similarity to GB:CAD86279.1; match to protein family HMM PF04430.
  
     0.624
AFE_3120
Membrane protein, putative.
  
     0.608
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.