Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2685Identified by match to protein family HMM PF00691. (183 aa)    
Predicted Functional Partners:
pal
Peptidoglycan-associated lipoprotein, putative; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
     0.763
omp40
Major outer membrane protein 40; Identified by similarity to GB:CAA10107.1; match to protein family HMM PF07396.
      
 0.704
AFE_1453
Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.
 
 
 0.672
tolB
Tol-pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.659
lolC
Lipoprotein releasing system transmembrane protein LolC; Identified by similarity to SP:P75956; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
  
 
   0.642
bamA
Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 0.573
tolQ
TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.524
AFE_0485
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
 
   
 0.523
AFE_2684
Identified by match to protein family HMM PF05658; match to protein family HMM PF05662; match to protein family HMM TIGR03304.
     
 0.522
AFE_2607
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
  
    0.478
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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