Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2690Type I secretion outer membrane protein, putative; Identified by match to protein family HMM PF02321. (598 aa)    
Predicted Functional Partners:
AFE_2692
Type I secretion membrane fusion protein, HlyD family; Identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843.
  
 
 0.781
AFE_2689
TonB family protein.
  
    0.773
AFE_0039
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
  
     0.743
AFE_0863
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
  
     0.732
AFE_2693
Type I secretion system ATPase; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846.
  
  
 0.729
AFE_2691
Hypothetical protein; Identified by glimmer; putative.
       0.675
AFE_2694
Conserved hypothetical protein; Identified by similarity to GB:CAE32332.1.
       0.675
AFE_0108
RND efflux system, outer membrane lipoprotein, NodT family; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
  
     0.673
AFE_1880
RND efflux system, outer membrane lipoprotein, NodT family; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
  
     0.672
AFE_0862
Drug resistance transporter, putative; Identified by match to protein family HMM PF00529.
 
   0.667
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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