Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2707Conserved hypothetical protein; Identified by similarity to GB:CAE42273.1; match to protein family HMM PF07811. (161 aa)    
Predicted Functional Partners:
AFE_2703
Pilus assembly protein CpaE, putative; Identified by similarity to GB:AAF40194.1.
 
  
 0.979
AFE_2705
Conserved hypothetical protein; Identified by similarity to GB:CAE32322.1; match to protein family HMM PF08666; match to protein family HMM TIGR03177.
 
  
 0.978
tadB
Tight adherence protein TadB, putative; Identified by similarity to GB:AAO10168.1; match to protein family HMM PF00482.
 
  
 0.975
tadC
Tight adherence protein TadC; Identified by similarity to GB:AAL92472.1; match to protein family HMM PF00482.
 
    0.934
AFE_2704
Bacterial type II/III secretion system protein; Identified by match to protein family HMM PF00263; Belongs to the bacterial secretin family.
 
  
 0.925
AFE_2699
Lipoprotein, putative; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
 
  
 0.912
tadA
Tight adherence protein TadA; Identified by similarity to GB:AAN75211.1; match to protein family HMM PF00437.
 
  
 0.905
AFE_2697
Conserved hypothetical protein; Identified by similarity to PIR:H83107.
 
    0.898
AFE_2708
Membrane protein, putative; Identified by match to protein family HMM PF01478.
  
  
 0.846
trbB
P-type conjugative transfer protein TrbB; Identified by similarity to SP:P54907; match to protein family HMM PF00437; match to protein family HMM TIGR02782.
 
  
 0.632
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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