nrdD protein (Acidithiobacillus ferrooxidans)

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Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0731	ndk	AFE_0731	AFE_1929	Deoxyguanosinetriphosphate triphosphohydrolase, putative; Identified by similarity to SP:Q8XV63; match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.901
AFE_0731	nrdD	AFE_0731	AFE_2718	Deoxyguanosinetriphosphate triphosphohydrolase, putative; Identified by similarity to SP:Q8XV63; match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.900
AFE_2719	nrdD	AFE_2719	AFE_2718	Conserved hypothetical protein; Identified by similarity to GB:AAP85991.1.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.940
AFE_2719	nrdG	AFE_2719	AFE_2720	Conserved hypothetical protein; Identified by similarity to GB:AAP85991.1.	Anaerobic ribonucleoside-triphosphate reductase, beta subunit; Identified by similarity to GB:CAA10042.1; match to protein family HMM PF04055; match to protein family HMM TIGR02495.	0.936
AFE_2719	queE	AFE_2719	AFE_0069	Conserved hypothetical protein; Identified by similarity to GB:AAP85991.1.	Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.815
dcd	dut	AFE_2660	AFE_0356	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.939
dcd	ndk	AFE_2660	AFE_1929	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.926
dcd	nrdD	AFE_2660	AFE_2718	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.903
dut	dcd	AFE_0356	AFE_2660	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	0.939
dut	ndk	AFE_0356	AFE_1929	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.921
dut	nrdD	AFE_0356	AFE_2718	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.934
dut	pyrG	AFE_0356	AFE_0847	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.404
maf-1	ndk	AFE_2953	AFE_1929	Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.905
maf-1	nrdD	AFE_2953	AFE_2718	Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.900
maf-1	pyrG	AFE_2953	AFE_0847	Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.906
ndk	AFE_0731	AFE_1929	AFE_0731	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Deoxyguanosinetriphosphate triphosphohydrolase, putative; Identified by similarity to SP:Q8XV63; match to protein family HMM PF01966; match to protein family HMM TIGR01353; Belongs to the dGTPase family. Type 2 subfamily.	0.901
ndk	dcd	AFE_1929	AFE_2660	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.	0.926
ndk	dut	AFE_1929	AFE_0356	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.921
ndk	maf-1	AFE_1929	AFE_2953	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.905
ndk	nrdD	AFE_1929	AFE_2718	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487.	0.911