Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
petB-2Ubiquinol--cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (404 aa)    
Predicted Functional Partners:
petA-2
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.999
petC-2
Ubiquinol--cytochrome c reductase, cytochrome c1 subunit; Identified by match to protein family HMM PF02167.
 0.999
petA-1
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.999
petC-1
Ubiquinol--cytochrome c reductase, cytochrome c1 subunit; Identified by match to protein family HMM PF02167.
 0.999
nuoM
NADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
 
 
 0.974
nuoH
NADH-quinone oxidoreductase, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
  
 
 0.970
coxA
Cytochrome c oxidase, aa3-type, subunit I; Identified by similarity to GB:CAA07035.1; match to protein family HMM PF00115.
 
 
 0.966
cyoC
Cytochrome o ubiquinol oxidase, subunit III; Identified by similarity to SP:P18402.
  
 
 0.964
coxB
Cytochrome c oxidase, aa3-type, subunit II; Identified by similarity to GB:CAA07034.1; match to protein family HMM PF00116.
 
 
 0.953
cyoB
Cytochrome o ubiquinol oxidase, subunit I; Identified by similarity to SP:P18401; match to protein family HMM PF00115; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.950
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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