Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
omp40Major outer membrane protein 40; Identified by similarity to GB:CAA10107.1; match to protein family HMM PF07396. (404 aa)    
Predicted Functional Partners:
AFE_2685
Identified by match to protein family HMM PF00691.
      
 0.704
typA
GTP-binding protein TypA; Identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394.
       0.472
AFE_0306
OmpA family protein; Identified by similarity to SP:Q05146; match to protein family HMM PF00691.
      
 0.449
mdoG
Periplasmic glucans biosynthesis protein, MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
      
 0.449
tetH
Tetrathionate hydrolase; Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
     
 0.444
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
      
 0.440
AFE_1396
Serine protease, DO/DeqQ family; Identified by similarity to SP:P09376; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
      
 0.440
AFE_1646
Serine protease, DO/DeqQ family; Identified by similarity to GB:AAK01318.1; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037.
      
 0.440
AFE_2849
Serine protease, DO/DeqQ family; Identified by similarity to GB:AAN67052.1; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
      
 0.440
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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