| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_1674 | prmC | AFE_1674 | AFE_2759 | Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.765 |
| AFE_2756 | AFE_2762 | AFE_2756 | AFE_2762 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | 0.668 |
| AFE_2756 | AFE_2763 | AFE_2756 | AFE_2763 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.604 |
| AFE_2756 | hemA | AFE_2756 | AFE_2761 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.737 |
| AFE_2756 | ispE | AFE_2756 | AFE_2764 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.547 |
| AFE_2756 | mutM | AFE_2756 | AFE_2758 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.737 |
| AFE_2756 | prfA | AFE_2756 | AFE_2760 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.780 |
| AFE_2756 | prmC | AFE_2756 | AFE_2759 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.737 |
| AFE_2756 | prsA | AFE_2756 | AFE_2766 | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.404 |
| AFE_2762 | AFE_2756 | AFE_2762 | AFE_2756 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | 0.668 |
| AFE_2762 | AFE_2763 | AFE_2762 | AFE_2763 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.836 |
| AFE_2762 | hemA | AFE_2762 | AFE_2761 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.652 |
| AFE_2762 | ispE | AFE_2762 | AFE_2764 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.805 |
| AFE_2762 | mutM | AFE_2762 | AFE_2758 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.594 |
| AFE_2762 | prfA | AFE_2762 | AFE_2760 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.682 |
| AFE_2762 | prmC | AFE_2762 | AFE_2759 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.623 |
| AFE_2762 | prsA | AFE_2762 | AFE_2766 | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.586 |
| AFE_2763 | AFE_2756 | AFE_2763 | AFE_2756 | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Conserved hypothetical protein; Identified by similarity to PIR:F83597. | 0.604 |
| AFE_2763 | AFE_2762 | AFE_2763 | AFE_2762 | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | 0.836 |
| AFE_2763 | hemA | AFE_2763 | AFE_2761 | Outer membrane lipoprotein LolB, putative; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.638 |
