Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_2782Cation efflux system protein, putative; Identified by similarity to SP:P77214. (120 aa)    
Predicted Functional Partners:
AFE_2428
Heavy metal efflux system protein, putative; Identified by similarity to SP:P77214.
  
  
 
0.901
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
  
     0.662
AFE_2434
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
 
   0.657
AFE_1949
Outer membrane heavy metal efflux protein, putative; Identified by similarity to SP:P11092; match to protein family HMM PF02321.
 
   0.625
AFE_2896
Identified by match to protein family HMM PF04932.
  
     0.614
AFE_1695
Conjugal transfer protein; Identified by similarity to SP:P54915; match to protein family HMM PF03524.
  
     0.603
AFE_1615
DNA primase TraC; Identified by similarity to SP:P27189; match to protein family HMM PF08401.
  
     0.595
AFE_1824
Membrane protein, putative.
  
     0.595
AFE_0398
Conserved hypothetical protein; Identified by similarity to GB:CAD15216.1.
  
     0.588
AFE_3189
Conserved domain protein; Identified by similarity to GB:CAD18424.1.
  
     0.582
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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