Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2803FMN reductase, NADPH-dependent; Identified by match to protein family HMM PF03358. (180 aa)    
Predicted Functional Partners:
AFE_2805
Conserved hypothetical protein; Identified by similarity to GB:CAD16379.1; match to protein family HMM PF07883.
  
    0.775
AFE_2804
Conserved hypothetical protein; Identified by similarity to GB:AAQ59281.1.
       0.773
AFE_2806
Conserved hypothetical protein; Identified by similarity to PIR:B83761.
       0.757
AFE_2807
Transcriptional regulator, putative; Identified by match to protein family HMM PF04299.
       0.726
AFE_2802
Multidrug resistance protein, SMR family; Identified by match to protein family HMM PF00893.
       0.608
AFE_2800
Identified by match to protein family HMM PF00903.
  
  
 0.483
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
 
   
 0.463
AFE_2801
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659.
       0.453
yghU
Glutathione S-transferase family protein YghU; Identified by similarity to SP:Q46845; match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.
  
    0.444
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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