Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2805Conserved hypothetical protein; Identified by similarity to GB:CAD16379.1; match to protein family HMM PF07883. (161 aa)    
Predicted Functional Partners:
AFE_3169
Conserved hypothetical protein; Identified by similarity to GB:CAD16379.1; match to protein family HMM PF07883.
  
 
  
0.900
AFE_2803
FMN reductase, NADPH-dependent; Identified by match to protein family HMM PF03358.
  
    0.775
AFE_2804
Conserved hypothetical protein; Identified by similarity to GB:AAQ59281.1.
       0.773
AFE_2806
Conserved hypothetical protein; Identified by similarity to PIR:B83761.
       0.757
AFE_2807
Transcriptional regulator, putative; Identified by match to protein family HMM PF04299.
       0.726
AFE_2802
Multidrug resistance protein, SMR family; Identified by match to protein family HMM PF00893.
       0.608
AFE_2800
Identified by match to protein family HMM PF00903.
  
    0.460
AFE_2801
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659.
  
    0.460
AFE_0786
Heme-utilization protein HutZ, putative; Identified by similarity to GB:AAG23392.1; match to protein family HMM PF01243.
  
     0.419
AFE_2799
Transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029.
 
     0.408
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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