Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2830Conserved hypothetical protein; Identified by similarity to GB:CAD85351.1. (142 aa)    
Predicted Functional Partners:
AFE_2831
Hypothetical protein; Identified by glimmer; putative.
 
     0.878
AFE_2829
Conserved hypothetical protein; Identified by similarity to PIR:H81856.
 
     0.825
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
       0.799
rumA
23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
       0.799
AFE_2827
Identified by match to protein family HMM PF03734.
       0.789
AFE_2826
Membrane protein, putative.
       0.773
AFE_1957
Conserved hypothetical protein; Identified by similarity to GB:AAN68501.1; match to protein family HMM PF04357.
 
     0.615
AFE_1958
Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244.
  
     0.554
AFE_0549
Conserved hypothetical protein; Identified by similarity to PIR:E82325.
  
   
 0.533
AFE_2316
Outer membrane lipoprotein Slp, putative; Identified by similarity to SP:P37194; match to protein family HMM PF03843.
  
     0.508
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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