| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_2846 | AFE_2848 | AFE_2846 | AFE_2848 | Hypothetical protein; Identified by glimmer; putative. | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.567 |
| AFE_2848 | AFE_2846 | AFE_2848 | AFE_2846 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Hypothetical protein; Identified by glimmer; putative. | 0.567 |
| AFE_2848 | dnaJ | AFE_2848 | AFE_2664 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.738 |
| AFE_2848 | gor | AFE_2848 | AFE_0366 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Glutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. | 0.921 |
| AFE_2848 | groEL | AFE_2848 | AFE_0542 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.847 |
| AFE_2848 | grpE | AFE_2848 | AFE_2666 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.860 |
| AFE_2848 | hslU | AFE_2848 | AFE_2748 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.821 |
| AFE_2848 | hslV | AFE_2848 | AFE_2747 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.838 |
| AFE_2848 | htpG | AFE_2848 | AFE_3158 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.793 |
| AFE_2848 | nrdA | AFE_2848 | AFE_2638 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Ribonucleotide-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.594 |
| AFE_2848 | trxB | AFE_2848 | AFE_0375 | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.820 |
| dnaJ | AFE_2848 | AFE_2664 | AFE_2848 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.738 |
| dnaJ | groEL | AFE_2664 | AFE_0542 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.968 |
| dnaJ | grpE | AFE_2664 | AFE_2666 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.992 |
| dnaJ | hslU | AFE_2664 | AFE_2748 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.929 |
| dnaJ | hslV | AFE_2664 | AFE_2747 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.886 |
| dnaJ | htpG | AFE_2664 | AFE_3158 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.992 |
| gor | AFE_2848 | AFE_0366 | AFE_2848 | Glutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.921 |
| gor | trxB | AFE_0366 | AFE_0375 | Glutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.484 |
| groEL | AFE_2848 | AFE_0542 | AFE_2848 | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Thioredoxin, putative; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.847 |
