| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_2421 | arsR | AFE_2421 | AFE_2859 | Cd(II)/Pb(II)-responsive transcriptional regulator; Identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02047. | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | 0.501 |
| arsB | arsC | AFE_2858 | AFE_2860 | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.915 |
| arsB | arsH | AFE_2858 | AFE_2857 | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | 0.959 |
| arsB | arsR | AFE_2858 | AFE_2859 | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | 0.924 |
| arsB | merC | AFE_2858 | AFE_2480 | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | Mercuric resistance protein MerC; Identified by similarity to SP:P22905; match to protein family HMM PF03203. | 0.440 |
| arsB | trxB | AFE_2858 | AFE_0375 | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.507 |
| arsC | arsB | AFE_2860 | AFE_2858 | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | 0.915 |
| arsC | arsH | AFE_2860 | AFE_2857 | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | 0.916 |
| arsC | arsR | AFE_2860 | AFE_2859 | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | 0.990 |
| arsC | trxB | AFE_2860 | AFE_0375 | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.466 |
| arsH | arsB | AFE_2857 | AFE_2858 | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | 0.959 |
| arsH | arsC | AFE_2857 | AFE_2860 | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.916 |
| arsH | arsR | AFE_2857 | AFE_2859 | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | 0.897 |
| arsH | hisA | AFE_2857 | AFE_3045 | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by similarity to SP:O35006; match to protein family HMM PF00977; match to protein family HMM TIGR00007. | 0.440 |
| arsH | merC | AFE_2857 | AFE_2480 | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | Mercuric resistance protein MerC; Identified by similarity to SP:P22905; match to protein family HMM PF03203. | 0.440 |
| arsR | AFE_2421 | AFE_2859 | AFE_2421 | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | Cd(II)/Pb(II)-responsive transcriptional regulator; Identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02047. | 0.501 |
| arsR | arsB | AFE_2859 | AFE_2858 | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | Arsenical pump membrane protein; Identified by similarity to GB:AAF69238.1; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935. | 0.924 |
| arsR | arsC | AFE_2859 | AFE_2860 | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.990 |
| arsR | arsH | AFE_2859 | AFE_2857 | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | Arsenical resistance protein ArsH; Has NADPH-dependent FMN reductase activity and high NADPH- dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH- dependent ferric reductase in vivo; Belongs to the ArsH family. | 0.897 |
| arsR | hisA | AFE_2859 | AFE_3045 | Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by similarity to SP:O35006; match to protein family HMM PF00977; match to protein family HMM TIGR00007. | 0.469 |