Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2862ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (592 aa)    
Predicted Functional Partners:
AFE_2863
ABC transporter, permease protein, putative; Identified by similarity to SP:P75775; match to protein family HMM PF01061.
    0.995
AFE_2864
ABC transporter, permease protein, putative; Identified by similarity to SP:P75774; match to protein family HMM PF01061.
    0.995
AFE_1604
ABC transporter, permease protein, putative; Identified by similarity to SP:P75775; match to protein family HMM PF01061.
    0.981
AFE_1603
ABC transporter, permease protein, putative; Identified by similarity to SP:P75774; match to protein family HMM PF01061.
    0.977
AFE_2861
Secretion protein, HlyD family; Identified by match to protein family HMM PF00529.
 
    0.950
AFE_2865
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1607
Secretion protein, HlyD family; Identified by match to protein family HMM PF00529.
 
    0.750
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.483
arsR
Transcriptional regulator, ArsR; Identified by match to protein family HMM PF01022.
       0.423
arsC
Arsenate reductase; Identified by similarity to GB:AAF69239.1; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.423
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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