Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_2875Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
AFE_0037
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.733
AFE_0761
Transcriptional regulator, LysR family; Identified by similarity to GB:AAK50330.1; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.708
AFE_0172
Transcriptional regulator, LysR family; Identified by similarity to SP:P25544; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.701
AFE_2874
Hypothetical protein; Identified by glimmer; putative.
       0.693
AFE_0866
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.682
AFE_0817
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.681
AFE_1993
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.670
AFE_2876
Conserved hypothetical protein; Identified by similarity to GB:AAM72097.1.
       0.540
AFE_1296
Transcriptional regulator, LysR family; Identified by similarity to SP:Q47083; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.524
cysB
Sulfur assimilation transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.523
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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