Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_2876Conserved hypothetical protein; Identified by similarity to GB:AAM72097.1. (207 aa)    
Predicted Functional Partners:
AFE_2557
Conserved hypothetical protein; Identified by similarity to GB:CAD85318.1; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family.
 
  
 0.844
sqr
Sulfide quinone reductase, putative; Identified by similarity to GB:AAF72963.1; match to protein family HMM PF07992.
 
     0.617
AFE_2875
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
       0.540
AFE_2529
Hypothetical protein; Identified by glimmer; putative.
  
     0.489
AFE_2874
Hypothetical protein; Identified by glimmer; putative.
       0.489
AFE_1659
Hypothetical protein; Identified by glimmer; putative.
  
     0.465
AFE_0743
Conserved domain protein.
  
     0.455
AFE_2600
Conserved hypothetical protein; Identified by similarity to SP:O29695; match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family.
 
  
 0.453
AFE_3117
Conserved hypothetical protein; Identified by similarity to SP:O29695; match to protein family HMM PF01206.
 
  
 0.453
isp2
Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754.
  
     0.400
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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