STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2879Conserved hypothetical protein; Identified by similarity to SP:P76395. (254 aa)    
Predicted Functional Partners:
AFE_2880
Von Willebrand factor type A domain protein; Identified by match to protein family HMM PF00092.
 
    0.963
AFE_2877
Conserved hypothetical protein; Identified by similarity to SP:P76393.
 
   
 0.955
pdhC
Pyruvate dehydrogenase complex, E2 and E3 components; Dihydrolipoamide acetyltransferase/dihydrolipoamide dehydrogenase; identified by similarity to PIR:C59237; match to protein family HMM PF00070; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM PF02852; match to protein family HMM PF07992.
  
 0.884
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM PF08669; match to protein family HMM TIGR00528.
   
  0.704
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.665
AFE_0707
Conserved hypothetical protein; Identified by similarity to PIR:AI1892.
  
 
   0.650
AFE_1053
Conserved domain protein; Identified by similarity to GB:AAF69908.1; match to protein family HMM PF01507.
  
     0.591
AFE_0711
NHL repeat protein; Identified by match to protein family HMM PF01436.
 
     0.555
AFE_0154
Identified by match to protein family HMM PF00230; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.509
AFE_1221
Modification methylase, putative; Identified by similarity to SP:P11409.
  
     0.499
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.