Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2888PIN domain protein; Identified by match to protein family HMM PF01850. (138 aa)    
Predicted Functional Partners:
AFE_2889
Transcriptional regulator, AbrB family; Identified by match to protein family HMM PF04014.
 
     0.948
vapC-4
PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
     0.633
AFE_2890
Hypothetical protein; Identified by glimmer; putative.
       0.572
AFE_1367
Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.
  
     0.519
AFE_0072
Conserved hypothetical protein; Identified by similarity to PIR:S76075.
  
     0.506
AFE_1579
Conserved hypothetical protein; Identified by similarity to GB:AAK52344.1.
  
     0.454
AFE_1578
PIN domain protein; Identified by match to protein family HMM PF01850.
  
     0.407
AFE_2891
Conserved hypothetical protein; Identified by similarity to GB:AAM41875.1.
       0.405
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.