Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amt-1Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836. (434 aa)    
Predicted Functional Partners:
glnB-2
Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P05826; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 0.967
glnK-1
Nitrogen regulatory protein P-II 2; Identified by similarity to SP:P38504; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 0.927
glnB-1
Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P05826; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 
 0.728
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
 
  
 0.696
glnK-2
Nitrogen regulatory protein P-II 2; Identified by similarity to SP:P38504; match to protein family HMM PF00543.
  
 
 0.689
AFE_2917
Glutamine amidotransferase class-I domain protein; Identified by match to protein family HMM PF00117.
 
   
 0.613
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P06711; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
  
  
 0.523
AFE_2914
Hypothetical protein; Identified by glimmer; putative.
       0.483
ntrB
Nitrogen regulation protein NR(II); Identified by similarity to SP:P06218; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF08448.
  
 
 0.482
AFE_0951
Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
      
 0.452
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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