| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_2930 | recB | AFE_2930 | AFE_2932 | Membrane protein, putative; Identified by similarity to GB:AAO81141.1; match to protein family HMM PF06736. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.492 |
| AFE_2930 | recC | AFE_2930 | AFE_2931 | Membrane protein, putative; Identified by similarity to GB:AAO81141.1; match to protein family HMM PF06736. | Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.492 |
| AFE_2930 | recD | AFE_2930 | AFE_2933 | Membrane protein, putative; Identified by similarity to GB:AAO81141.1; match to protein family HMM PF06736. | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.489 |
| csf1 | csf3 | AFE_1038 | AFE_1040 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | 0.934 |
| csf1 | csf4 | AFE_1038 | AFE_1037 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.876 |
| csf1 | recB | AFE_1038 | AFE_2932 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.475 |
| csf1 | rpsA | AFE_1038 | AFE_0903 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.443 |
| csf1 | ruvC | AFE_1038 | AFE_0060 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.440 |
| csf3 | csf1 | AFE_1040 | AFE_1038 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | 0.934 |
| csf3 | csf4 | AFE_1040 | AFE_1037 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.876 |
| csf3 | recB | AFE_1040 | AFE_2932 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.723 |
| csf3 | ruvC | AFE_1040 | AFE_0060 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.723 |
| csf4 | csf1 | AFE_1037 | AFE_1038 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | 0.876 |
| csf4 | csf3 | AFE_1037 | AFE_1040 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | 0.876 |
| csf4 | recA | AFE_1037 | AFE_0932 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.587 |
| csf4 | recB | AFE_1037 | AFE_2932 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.764 |
| csf4 | recD | AFE_1037 | AFE_2933 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.789 |
| csf4 | ruvC | AFE_1037 | AFE_0060 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.752 |
| recA | csf4 | AFE_0932 | AFE_1037 | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.587 |
| recA | recB | AFE_0932 | AFE_2932 | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.510 |
